College football picks: Predictions against the spread, odds, betting lines for top 25 games in Week 4

The article provides predictions and analysis for the top 25 college football games in Week 4 of the 2025 season. It covers the spreads, odds, and betting lines for these matchups. The article highlights key games, including a top-10 showdown between two undefeated teams, a ranked clash between conference rivals, and a battle of two teams looking to bounce back from early-season losses. The analysis includes factors such as team statistics, player injuries, and recent performances to determine the most likely outcomes against the spread. It also provides insights into the potential impact of these games on the national landscape and the playoff race. The article aims to offer readers a comprehensive preview of the week's most significant college football games, allowing them to make informed decisions when it comes to betting or following the action.
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