Sports9/20/2025CBS Sports

Where to watch Cardinals vs. 49ers: TV channel, live stream, prediction, pick, odds, spread


                        Where to watch Cardinals vs. 49ers: TV channel, live stream, prediction, pick, odds, spread

The Arizona Cardinals will face the San Francisco 49ers in a crucial NFC West matchup. Both teams enter the game with 2-0 records, and the winner will take the lead in the division. The game will be broadcast on FOX, with the kickoff scheduled for 4:25 PM ET. Fans can also stream the game live on the FOX Sports app or NFL Sunday Ticket. Oddsmakers have the 49ers as 1-point favorites at home, with the over/under set at 43.5 points. The game is expected to be a close and competitive affair, with both teams boasting strong offenses and defenses. The Cardinals, led by quarterback Kyler Murray, will look to continue their hot start and solidify their position as one of the top teams in the NFC. The 49ers, led by quarterback Jimmy Garoppolo, will aim to bounce back from their recent injury woes and maintain their place at the top of the division.

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