Sports10/10/2025CBS Sports

Michigan vs. USC prediction, pick, odds, spread: No. 15 Wolverines, Trojans meet in crucial Big Ten clash


                        Michigan vs. USC prediction, pick, odds, spread: No. 15 Wolverines, Trojans meet in crucial Big Ten clash

The upcoming matchup between No. 15 Michigan and USC is set to be a crucial Big Ten clash. The two teams faced off last year in a thrilling contest, and this year's game promises to be just as exciting. Michigan, led by head coach Jim Harbaugh, is coming into the game with a 2-0 record after wins against Colorado State and Hawaii. Meanwhile, USC, under the leadership of Lincoln Riley, has also started the season strong with a 2-0 record. Both teams have talented rosters and are expected to put on a great show for the fans. The game's outcome will be crucial for the teams' standings in their respective conferences. The article also includes predictions, picks, odds, and spreads for the game, but I have not included those details in this summary as they are not the most important facts from the article.

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