Sperm From Older Men Have More Genetic Mutations

Researchers have found that sperm from older men contain more genetic mutations compared to younger men. The study, published in the journal Science, analyzed the DNA of sperm samples from 872 men between the ages of 15 and 44. The findings show that the number of mutations in sperm increases by approximately two per year as men age. This could potentially increase the risk of passing on genetic disorders or developmental issues to their children. The study emphasizes the importance of understanding the relationship between paternal age and the genetic health of offspring. While the overall risk remains low, the accumulation of mutations in sperm over time highlights the need for men to consider their age when planning a family. The researchers suggest that as men get older, they may need to undergo additional genetic testing or consider alternative family planning options to reduce the potential impact of these age-related genetic changes.