Bills vs. Ravens prediction, odds, start time: 2025 NFL Week 1 Sunday Night Football picks from advanced model

The SportsLine projection model has released its picks for the 2025 NFL Week 1 Sunday Night Football game between the Baltimore Ravens and the Buffalo Bills. The model has analyzed various factors, including team statistics, player performance, and historical matchups, to provide predictions for the outcome of the game. According to the model, the Bills are favored to win the game with a spread of -3.5 points. The model also suggests that the game will be a high-scoring affair, with an over/under of 54.5 points. The projected final score is Bills 31, Ravens 27. The game is set to kick off at 8:20 PM ET on Sunday, September 7, 2025, at Highmark Stadium in Buffalo, New York. Fans and viewers can tune in to NBC to watch the highly anticipated matchup between these two powerhouse teams.
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