← All storiesHealthDeveloping story

This could be why your weight-loss medication isn’t delivering results

This material may not be published, broadcast, rewritten, or redistributed. ©2026 FOX News Network, LLC. All rights reserved. Quotes displayed in real-time or delayed by at least 15 minutes. Market data provided by Factset. Powered and implemented by FactSet Digital Solutions. Legal Statement. Mutual Fund and ETF data provided by LSEG. Fox News senior medical analyst Dr. Marc Siegel discusses the benefits and risks of GLP-1 medications on 'Fox & Friends Weekend.' The skyrocketing popularity of GLP-1 receptor agonists has transformed the weight-loss industry, but not all shots are created equal in terms of how they work. A study published in Nature investigated how genes affect the success of modern weight-loss drugs — specifically, GLP-1s like semaglutide and tirzepatide. In analyzing genetic data and self-reported weight loss from over 27,000 users, researchers pinpointed a specific variation in the GLP-1 receptor gene (GLP1R) that acts as a "booster" for the drug’s effectiveness. POPULAR WEIGHT-LOSS MEDICATIONS LINKED TO HIDDEN SIDE EFFECTS, STUDY FINDS Individuals carrying one copy of this variant lost an average of 1.6 pounds more than those without it, according to the finding

2
updates in timeline
1
distinct sources
10 days
story span
Apr 26, 2026
latest update

Apr 16, 2026 → Apr 26, 2026

LATEST DEVELOPMENT
Apr 26, 2026·Fox NewsT2 · Outlet report
Patients taking weight-loss drugs often make 5 critical mistakes, doctor warns

This material may not be published, broadcast, rewritten, or redistributed. ©2026 FOX News Network, LLC. All rights reserved. Quotes displayed in real-time or delayed by at least 15 minutes. Market data provided by Factset. Powered and…

Read original at Fox News →
ACTIVITY · UPDATES PER MONTH
Apr 26

2 updates from 1 source over 10 days.

Showing 2 of 2 updates

Timeline (2 updates)

April 2026

2 updates
Apr 26, 2026·Fox NewsT2 · Outlet reportLATEST
Patients taking weight-loss drugs often make 5 critical mistakes, doctor warns

This material may not be published, broadcast, rewritten, or redistributed. ©2026 FOX News Network, LLC. All rights reserved. Quotes displayed in real-time or delayed by at least 15 minutes. Market data provided by…

Read original at Fox News →
Apr 16, 2026·Fox NewsT2 · Outlet reportOPENING
This could be why your weight-loss medication isn’t delivering results

This material may not be published, broadcast, rewritten, or redistributed. ©2026 FOX News Network, LLC. All rights reserved. Quotes displayed in real-time or delayed by at least 15 minutes. Market data provided by…

Read original at Fox News →

Sources & evidence (2)

What this story stands on. Tier 0 is a primary record or the subject's own words; higher tiers must be attributed, never stated as bare fact.

T2 · Outlet report× 2
COVERAGE BY SOURCE
Fox News 2
STRONGEST EVIDENCE
T2 · Outlet reportFox NewsApr 26, 2026

This material may not be published, broadcast, rewritten, or redistributed. ©2026 FOX News Network, LLC. All rights reserved. Quotes displayed in real-time or delayed by at least 15 minutes. Market data provided by Factset. Powered and…

View source →
T2 · Outlet reportFox NewsApr 16, 2026

This material may not be published, broadcast, rewritten, or redistributed. ©2026 FOX News Network, LLC. All rights reserved. Quotes displayed in real-time or delayed by at least 15 minutes. Market data provided by Factset. Powered and…

View source →

Tier key: T0 = Primary source · T1 = Wire · T2 = Outlet report · T3 = Commentary

Related stories

HealthT2 · Outlet report

Vitamin supplement may delay diabetes in select groups, researchers say

This material may not be published, broadcast, rewritten, or redistributed. ©2026 FOX News Network, LLC. All rights reserved. Quotes displayed in real-time or delayed by at least…

1 update1 source
Apr 30, 2026
Latest: Vitamin supplement may delay diabetes in select groups, researchers say · Fox News
GeneralT2 · Outlet report

US states drop Medicaid coverage of GLP-1 weight-loss drugs as demand rises

Experts say any short-term financial benefit will be outweighed by long-term health costs related to obesity Faced with high demand for GLP-1 drugs, some American cities and…

1 update1 source
Apr 14, 2026
Latest: US states drop Medicaid coverage of GLP-1 weight-loss drugs as demand rises · The Guardian
HealthT2 · Outlet report

The ‘Wild West’ of peptides is booming. Here’s what’s real, what’s risky and what’s next | CNN

In the early 2020s, interest in GLP-1 weight loss drugs exploded. Now, as we move deeper into the decade, a new buzzword is taking over: peptides. And the demand for peptides…

1 update1 source
Apr 13, 2026
Latest: The ‘Wild West’ of peptides is booming. Here’s what’s real, what’s risky and what’s next | CNN · CNN
BusinessT2 · Outlet report

Plus-size fashionistas worry GLP1-s will make it even harder for them to shop | CNN Business

Buying clothes has always been challenging for Ann Lindsay. As a plus-sized 41-year-old, she finds many stores’ plus-size offerings too matronly or too expensive. Lately, it’s…

1 update1 source
Apr 5, 2026
Latest: Plus-size fashionistas worry GLP1-s will make it even harder for them to shop | CNN Business · CNN
GeneralT2 · Outlet report

Scary news, financial fears, world chaos? Easter offers a lesson for all of us

This material may not be published, broadcast, rewritten, or redistributed. ©2026 FOX News Network, LLC. All rights reserved. Quotes displayed in real-time or delayed by at least…

1 update1 source
Apr 3, 2026
Latest: Scary news, financial fears, world chaos? Easter offers a lesson for all of us · Fox News
HealthT2 · Outlet report

Breakthrough ALS study launches as drug aims to slow disease progression

This material may not be published, broadcast, rewritten, or redistributed. ©2026 FOX News Network, LLC. All rights reserved. Quotes displayed in real-time or delayed by at least…

1 update1 source
Apr 3, 2026
Latest: Breakthrough ALS study launches as drug aims to slow disease progression · Fox News