General5/12/2026•The Guardian

Marty Makary departs FDA after clashes with Trump over fruit-flavored vapes

Marty Makary departs FDA after clashes with Trump over fruit-flavored vapes

Kyle Diamantas, a top official at the agency, will replace Makary and serve as acting FDA commissioner Sign up for the Breaking News US newsletter email Marty Makary resigned from his position as commissioner of the US Food and Drug Administration (FDA) on Tuesday, concluding a 13-month tenure at the regulatory agency that frequently drew the ire of the White House, Congress, industry and the public, Donald Trump confirmed on Tuesday. Kyle Diamantas, who previously worked as the top food official at the agency setting the strategic direction and operations for food policy in the US, will be Makary’s acting replacement. Trump called Diamantas a “very talented person” in a Truth Social post confirming he’d be Makary’s temporary replacement. “Please accept my resignation, effective today. During my tenure, I announced 50 major FDA reforms. Joe Biden’s FDA had none. I’m extremely proud that we have reduced drug review times from a year to 1-2 months, wrote new guidance to advance psychedelics, introduced a new ‘plausible mechanism’ pathway for rare disease drugs, and changed estrogen labels to tell women the truth about menopausal hormone replacement. It’s been the honor of a lifetime

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