The mother of a six-year-old girl who had life-changing eye gene therapy says it is "like someone waved a magic wand and restored her sight in the dark". Saffie Sandford, from Stevenage, has the rare inherited condition Leber's Congenital Amaurosis (LCA), which prevents cells in the eye from making a specific protein needed for normal vision. After tests were carried out at Moorfields Eye Hospital in London, she was treated at Great Ormond Street Hospital (GOSH) and underwent Luxturna therapy. Her mother Lisa said the family had been told Saffie would have been "blind by the age of 30" without treatment. GOSH said the treatment had been the first of its kind for one of the genetic causes of LCA, with Saffie having one procedure on one eye in April 2025 and the other in September. The one-off therapy contains a healthy copy of the gene, which is injected directly into each eye. From the age of two, Saffie has worn glasses after being told she was short-sighted. At five, she was diagnosed with LCA when her parents noticed she was struggling to see in the dark. Babies and children with the condition have low vision in daylight and no vision in low light - and can lose their sight comp
Apr 23, 2026 → Apr 23, 2026
The mother of a six-year-old girl who had life-changing eye gene therapy says it is "like someone waved a magic wand and restored her sight in the dark". Saffie Sandford, from Stevenage, has the rare inherited condition Leber's Congenital…
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The mother of a six-year-old girl who had life-changing eye gene therapy says it is "like someone waved a magic wand and restored her sight in the dark". Saffie Sandford, from Stevenage, has the rare inherited condition…
Read original at BBC →What this story stands on. Tier 0 is a primary record or the subject's own words; higher tiers must be attributed, never stated as bare fact.
The mother of a six-year-old girl who had life-changing eye gene therapy says it is "like someone waved a magic wand and restored her sight in the dark". Saffie Sandford, from Stevenage, has the rare inherited condition Leber's Congenital…
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